
High-resolution electrophysiology meets high-throughput drug discovery.
Plasmonica
Plasmonica
Plasmonica Bio is a drug discovery engine leveraging next-generation optical electrophysiology to accelerate the development of therapies for diseases of the nervous system. Headquartered near the San Francisco Bay Area, Plasmonica partners with pharma and biotech companies to power breakthroughs in CNS drug discovery, toxicology, and mechanistic neuroscience.
Context
92% of neurotherapeutics entering clinical trials fail, raising the average cost of making a successful drug to $765M.

The preclinical market has an unmet need for tools with higher resolution, throughput, and bandwidth representing a market size of over $450M by 2030.

Approach
We introduce a series of assays based on a new sensing mechanism that enables:

• Throughput for any format
• 10x better resolution than competitors
Technology
Plasmonica utilizes a new technique that senses neural signals using electroplasmonic devices.

This technology was developed by the Plasmonica team and is licensed from UC Santa Cruz.
Team

Neil Hardy, PhD
CEO